rs110402
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
child abuse behavior
|
|
0.030 |
GeneticVariation |
BEFREE |
While GSK561679 was not superior to placebo overall, it was associated with a significantly stronger symptom reduction in a subset of patients with probable CRF system hyperactivity, i.e., patients with child abuse and CRHR1 SNP rs110402 GG carriers.
|
30390684 |
2018 |
rs17689918
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Anxiety
|
|
0.010 |
GeneticVariation |
BEFREE |
When investigating neural correlates underlying this association in patients with PD using functional magnetic resonance imaging, risk allele carriers of rs17689918 showed aberrant differential conditioning predominantly in the bilateral prefrontal cortex and safety signal processing in the amygdalae, arguing for predominant generalization of fear and hence anxious apprehension.
|
26324098 |
2016 |
rs242941
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Depressive disorder
|
|
0.030 |
GeneticVariation |
BEFREE |
When all subjects were grouped based on family history of mental illness, there was a statistically significant association of CRHR1 rs242941 with family history regardless of depression status (P = 0.043).
|
26518448 |
2015 |
rs242941
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Mental Depression
|
|
0.020 |
GeneticVariation |
BEFREE |
When all subjects were grouped based on family history of mental illness, there was a statistically significant association of CRHR1 rs242941 with family history regardless of depression status (P = 0.043).
|
26518448 |
2015 |
rs242941
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Depressed mood
|
|
0.020 |
GeneticVariation |
BEFREE |
When all subjects were grouped based on family history of mental illness, there was a statistically significant association of CRHR1 rs242941 with family history regardless of depression status (P = 0.043).
|
26518448 |
2015 |
rs242941
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Mental disorders
|
|
0.010 |
GeneticVariation |
BEFREE |
When all subjects were grouped based on family history of mental illness, there was a statistically significant association of CRHR1 rs242941 with family history regardless of depression status (P = 0.043).
|
26518448 |
2015 |
rs16940665
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.
|
21738487 |
2011 |
rs16940668
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.
|
21738487 |
2011 |
rs16940674
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.
|
21738487 |
2011 |
rs16940676
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.
|
21738487 |
2011 |
rs17425752
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.
|
21738487 |
2011 |
rs1876828
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.
|
21738487 |
2011 |
rs1876829
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.
|
21738487 |
2011 |
rs1876830
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.
|
21738487 |
2011 |
rs2316765
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.
|
21738487 |
2011 |
rs4482334
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.
|
21738487 |
2011 |
rs4525537
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.
|
21738487 |
2011 |
rs878887
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.
|
21738487 |
2011 |
rs878888
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.
|
21738487 |
2011 |
rs110402
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
child abuse behavior
|
|
0.030 |
GeneticVariation |
BEFREE |
We then extended our previously reported interaction with both a CRHR1 SNP (rs110402) and TCA haplotype interacting with child abuse to predict current symptoms (N = 1,059; P = 0.0089).
|
20029939 |
2010 |
rs110402
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Anxiety Disorders
|
|
0.030 |
GeneticVariation |
BEFREE |
We observed interactions between trait anxiety and rs7209436 and rs110402 in CRHR1 in association with baseline cortisol (p LRT = 0.0272 and p LRT = 0.0483, respectively).
|
23274505 |
2013 |
rs110402
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Anxiety
|
|
0.020 |
GeneticVariation |
BEFREE |
We observed interactions between trait anxiety and rs7209436 and rs110402 in CRHR1 in association with baseline cortisol (p LRT = 0.0272 and p LRT = 0.0483, respectively).
|
23274505 |
2013 |
rs7209436
|
CRHR1;LINC02210-CRHR1
|
Anxiety Disorders
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed interactions between trait anxiety and rs7209436 and rs110402 in CRHR1 in association with baseline cortisol (p LRT = 0.0272 and p LRT = 0.0483, respectively).
|
23274505 |
2013 |
rs7209436
|
CRHR1;LINC02210-CRHR1
|
Anxiety
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed interactions between trait anxiety and rs7209436 and rs110402 in CRHR1 in association with baseline cortisol (p LRT = 0.0272 and p LRT = 0.0483, respectively).
|
23274505 |
2013 |
rs17689918
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Antisocial behavior
|
|
0.010 |
GeneticVariation |
BEFREE |
We assess the effects of CRHR1 variant (rs17689918)-by-environment interactions on emotionality and behavioral traits, including anxiety, depression, aggression and antisocial behaviors.
|
29772307 |
2018 |